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Improving the power of clinical trials of rheumatoid arthritis by using data on continuous scales when analysing response rates: an application of the augmented binary method

Objective. In clinical trials of RA, it is common to assess effectiveness using end points based upon dichotomized continuous measures of disease activity, which classify patients as responders or non-responders. Although dichotomization generally loses statistical power, there are good clinical rea...

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Detalles Bibliográficos
Autores principales: Wason, James M. S., Jenkins, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034221/
https://www.ncbi.nlm.nih.gov/pubmed/27338084
http://dx.doi.org/10.1093/rheumatology/kew263