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CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells

The molecular mechanisms underlying mesodermal and cardiac specification from embryonic stem cells (ESCs) are not fully understood. Here, we showed that the BTB domain-containing zinc finger protein CIBZ is expressed in mouse ESCs but is dramatically downregulated during ESC differentiation. CIBZ de...

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Detalles Bibliográficos
Autores principales: Kotoku, Tomomi, Kosaka, Koji, Nishio, Miki, Ishida, Yasumasa, Kawaichi, Masashi, Matsuda, Eishou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034229/
https://www.ncbi.nlm.nih.gov/pubmed/27659197
http://dx.doi.org/10.1038/srep34188