New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes

Shwachman-Diamond syndrome (SDS) is an inherited disease caused by mutations of a gene encoding for SBDS protein. So far little is known about SBDS exact function. SDS patients present several hematological disorders, including neutropenia and myelodysplastic syndrome (MDS), with increased risk of l...

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Detalles Bibliográficos
Autores principales: Bezzerri, Valentino, Vella, Antonio, Calcaterra, Elisa, Finotti, Alessia, Gasparello, Jessica, Gambari, Roberto, Assael, Baroukh Maurice, Cipolli, Marco, Sorio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034238/
https://www.ncbi.nlm.nih.gov/pubmed/27658964
http://dx.doi.org/10.1038/srep33165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034238/
https://www.ncbi.nlm.nih.gov/pubmed/27658964
http://dx.doi.org/10.1038/srep33165

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