Cargando…

Liprin-α1 and ERC1 control cell edge dynamics by promoting focal adhesion turnover

Liprin-α1 and ERC1 are interacting scaffold proteins regulating the motility of normal and tumor cells. They act as part of plasma membrane-associated platforms at the edge of motile cells to promote protrusion by largely unknown mechanisms. Here we identify an amino-terminal region of the liprin-α1...

Descripción completa

Detalles Bibliográficos
Autores principales: Astro, Veronica, Tonoli, Diletta, Chiaretti, Sara, Badanai, Sabrina, Sala, Kristyna, Zerial, Marino, de Curtis, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034239/
https://www.ncbi.nlm.nih.gov/pubmed/27659488
http://dx.doi.org/10.1038/srep33653