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Transmembrane Helices Tilt, Bend, Slide, Torque, and Unwind between Functional States of Rhodopsin

The seven-helical bundle of rhodopsin and other G-protein coupled receptors undergoes structural rearrangements as the transmembrane receptor protein is activated. These structural changes are known to involve tilting and bending of various transmembrane helices. However, the cause and effect relati...

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Detalles Bibliográficos
Autores principales: Ren, Zhong, Ren, Peter X., Balusu, Rohith, Yang, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034245/
https://www.ncbi.nlm.nih.gov/pubmed/27658480
http://dx.doi.org/10.1038/srep34129