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Transmission of survival signals through Delta-like 1 on activated CD4(+) T cells

Notch expressed on CD4(+) T cells transduces signals that mediate their effector functions and survival. Although Notch signaling is known to be cis-inhibited by Notch ligands expressed on the same cells, the role of Notch ligands on T cells remains unclear. In this report we demonstrate that the CD...

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Detalles Bibliográficos
Autores principales: Furukawa, Takahiro, Ishifune, Chieko, Tsukumo, Shin-ichi, Hozumi, Katsuto, Maekawa, Yoichi, Matsui, Naoko, Kaji, Ryuji, Yasutomo, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034251/
https://www.ncbi.nlm.nih.gov/pubmed/27659682
http://dx.doi.org/10.1038/srep33692