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Mitigation of indomethacin-induced gastrointestinal damages in fat-1 transgenic mice via gate-keeper action of ω-3-polyunsaturated fatty acids

Non-steroidal anti-inflammatory drugs (NSAIDs) damage the gastrointestinal (GI) epithelial cell membranes by inducing several signals through lipid raft organization after membrane incorporation, whereas ω-3 polyunsaturated fatty acids (PUFAs) relieve inflammation, reduce oxidative stress, and provi...

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Detalles Bibliográficos
Autores principales: Han, Young-Min, Park, Jong-Min, Kang, Jing X., Cha, Ji-Young, Lee, Ho-Jae, Jeong, Migeyong, Go, Eun-Jin, Hahm, Ki Baik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034283/
https://www.ncbi.nlm.nih.gov/pubmed/27658533
http://dx.doi.org/10.1038/srep33992