Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers

Based on transcriptomic analyses of thousands of samples from The Cancer Genome Atlas, we report that expression of constitutive proteasome (CP) genes (PSMB5, PSMB6, PSMB7) and immunoproteasome (IP) genes (PSMB8, PSMB9, PSMB10) is increased in most cancer types. In breast cancer, expression of IP ge...

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Detalles Bibliográficos
Autores principales: Rouette, Alexandre, Trofimov, Assya, Haberl, David, Boucher, Geneviève, Lavallée, Vincent-Philippe, D’Angelo, Giovanni, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Perreault, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034284/
https://www.ncbi.nlm.nih.gov/pubmed/27659694
http://dx.doi.org/10.1038/srep34019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034284/
https://www.ncbi.nlm.nih.gov/pubmed/27659694
http://dx.doi.org/10.1038/srep34019

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