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Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels

Eukaryotic cyclic nucleotide-modulated (CNM) ion channels perform various physiological roles by opening in response to cyclic nucleotides binding to a specialized cyclic nucleotide-binding domain. Despite progress in structure-function analysis, the conformational rearrangements underlying the gati...

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Detalles Bibliográficos
Autores principales: Rangl, Martina, Miyagi, Atsushi, Kowal, Julia, Stahlberg, Henning, Nimigean, Crina M., Scheuring, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034309/
https://www.ncbi.nlm.nih.gov/pubmed/27647260
http://dx.doi.org/10.1038/ncomms12789