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Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels
Eukaryotic cyclic nucleotide-modulated (CNM) ion channels perform various physiological roles by opening in response to cyclic nucleotides binding to a specialized cyclic nucleotide-binding domain. Despite progress in structure-function analysis, the conformational rearrangements underlying the gati...
Autores principales: | Rangl, Martina, Miyagi, Atsushi, Kowal, Julia, Stahlberg, Henning, Nimigean, Crina M., Scheuring, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034309/ https://www.ncbi.nlm.nih.gov/pubmed/27647260 http://dx.doi.org/10.1038/ncomms12789 |
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