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Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro

Telomerase is the enzyme involved in extending telomeric DNA. Control of telomerase activity by modulating its access to chromosome ends is one of the most important fundamental mechanisms. This study established an in vitro yeast telomerase reconstitution system that resembles telomere replication...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Fan, Lu, Chia-Ying, Lin, Yi-Chien, Yu, Tai-Yuan, Chang, Chun-Ping, Li, Jing-Ru, Li, Hung-Wen, Lin, Jing-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034320/
https://www.ncbi.nlm.nih.gov/pubmed/27659693
http://dx.doi.org/10.1038/srep34104