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Delayed glial clearance of degenerating axons in aged Drosophila is due to reduced PI3K/Draper activity
Advanced age is the greatest risk factor for neurodegenerative disorders, but the mechanisms that render the senescent brain vulnerable to disease are unclear. Glial immune responses provide neuroprotection in a variety of contexts. Thus, we explored how glial responses to neurodegeneration are alte...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034330/ https://www.ncbi.nlm.nih.gov/pubmed/27647497 http://dx.doi.org/10.1038/ncomms12871 |