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Enantioselective cascade biocatalysis for deracemization of 2-hydroxy acids using a three-enzyme system

BACKGROUND: Enantiopure 2-hydroxy acids are key intermediates for the synthesis of pharmaceuticals and fine chemicals. We present an enantioselective cascade biocatalysis using recombinant microbial cells for deracemization of racemic 2-hydroxy acids that allows for efficient production of enantiopu...

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Detalles Bibliográficos
Autores principales: Xue, Ya-Ping, Zeng, Hao, Jin, Xiao-Lu, Liu, Zhi-Qiang, Zheng, Yu-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034429/
https://www.ncbi.nlm.nih.gov/pubmed/27659410
http://dx.doi.org/10.1186/s12934-016-0560-1