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Analysis of gene copy number changes in tumor phylogenetics

BACKGOUND: Evolution of cancer cells is characterized by large scale and rapid changes in the chromosomal  landscape. The fluorescence in situ hybridization (FISH) technique provides a way to measure the copy numbers of preselected genes in a group of cells and has been found to be a reliable source...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Lin, Yu, Rajan, Vaibhav, Hoskins, William, Feng, Bing, Tang, Jijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034472/
https://www.ncbi.nlm.nih.gov/pubmed/27688796
http://dx.doi.org/10.1186/s13015-016-0088-2