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Acute hyperglycemia suppresses left ventricular diastolic function and inhibits autophagic flux in mice under prohypertrophic stimulation

BACKGROUND: Left ventricular (LV) dysfunction is closely associated with LV hypertrophy or diabetes, as well as insufficient autophagic flux. Acute or chronic hyperglycemia is a prognostic factor for patients with myocardial infarction. However, the effect of acute hyperglycemia on LV dysfunction of...

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Detalles Bibliográficos
Autores principales: Xie, Jiahe, Cui, Kai, Hao, Huixin, Zhang, Yingxue, Lin, Hairuo, Chen, Zhenhuan, Huang, Xiaobo, Cao, Shiping, Liao, Wangjun, Bin, Jianping, Kitakaze, Masafumi, Liao, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034479/
https://www.ncbi.nlm.nih.gov/pubmed/27659110
http://dx.doi.org/10.1186/s12933-016-0452-z