Osteocalcin is necessary and sufficient to maintain muscle mass in older mice

OBJECTIVE: A decrease in muscle protein turnover and therefore in muscle mass is a hallmark of aging. Because the circulating levels of the bone-derived hormone osteocalcin decline steeply during aging in mice, monkeys and humans we asked here whether this hormone might regulate muscle mass as mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Mera, Paula, Laue, Kathrin, Wei, Jianwen, Berger, Julian Meyer, Karsenty, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034485/
https://www.ncbi.nlm.nih.gov/pubmed/27689017
http://dx.doi.org/10.1016/j.molmet.2016.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034485/
https://www.ncbi.nlm.nih.gov/pubmed/27689017
http://dx.doi.org/10.1016/j.molmet.2016.07.002

Ejemplares similares