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Inhibition of RORα/γ suppresses atherosclerosis via inhibition of both cholesterol absorption and inflammation
OBJECTIVE: Cardiovascular diseases (CVDs) are the leading cause of mortality in Western countries. Atherosclerosis is a multi-step inflammatory disease characterized at early stages by accumulation of cholesterol in the arterial wall followed by recruitment of immune cells. We sought to determine if...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034492/ https://www.ncbi.nlm.nih.gov/pubmed/27689012 http://dx.doi.org/10.1016/j.molmet.2016.07.001 |