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solveME: fast and reliable solution of nonlinear ME models

BACKGROUND: Genome-scale models of metabolism and macromolecular expression (ME) significantly expand the scope and predictive capabilities of constraint-based modeling. ME models present considerable computational challenges: they are much (>30 times) larger than corresponding metabolic reconstr...

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Detalles Bibliográficos
Autores principales: Yang, Laurence, Ma, Ding, Ebrahim, Ali, Lloyd, Colton J., Saunders, Michael A., Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034503/
https://www.ncbi.nlm.nih.gov/pubmed/27659412
http://dx.doi.org/10.1186/s12859-016-1240-1