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A HuR/TGF-β1 feedback circuit regulates airway remodeling in airway smooth muscle cells

BACKGROUND: Asthma is a worldwide health burden with an alarming prevalence. For years, asthma-associated airway injury remains elusive. Transforming growth factor β1 (TGF-β1) is a pleiotropic cytokine that has been shown to be involved in the synthesis of the matrix molecules associated with airway...

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Detalles Bibliográficos
Autores principales: Wang, Na, Yan, Di, Liu, Yi, Liu, Yao, Gu, Xianmin, Sun, Jian, Long, Fei, Jiang, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034516/
https://www.ncbi.nlm.nih.gov/pubmed/27658983
http://dx.doi.org/10.1186/s12931-016-0437-1