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Nonvitamin K antagonist oral anticoagulant activity: challenges in measurement and reversal

BACKGROUND: Four nonvitamin K antagonist oral anticoagulants (NOACs) are approved for the prevention of stroke in patients with nonvalvular atrial fibrillation and for the treatment of venous thromboembolism. These include the direct thrombin inhibitor dabigatran and the direct factor Xa inhibitors...

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Detalles Bibliográficos
Autores principales: Brown, Karen S., Zahir, Hamim, Grosso, Michael A., Lanz, Hans J., Mercuri, Michele F., Levy, Jerrold H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034528/
https://www.ncbi.nlm.nih.gov/pubmed/27659071
http://dx.doi.org/10.1186/s13054-016-1422-2