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PRKCQ promotes oncogenic growth and anoikis resistance of a subset of triple-negative breast cancer cells

BACKGROUND: The protein kinase C (PKC) family comprises distinct classes of proteins, many of which are implicated in diverse cellular functions. Protein tyrosine kinase C theta isoform (PRKCQ)/PKCθ, a member of the novel PKC family, may have a distinct isoform-specific role in breast cancer. PKCθ i...

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Detalles Bibliográficos
Autores principales: Byerly, Jessica, Halstead-Nussloch, Gwyneth, Ito, Koichi, Katsyv, Igor, Irie, Hanna Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034539/
https://www.ncbi.nlm.nih.gov/pubmed/27663795
http://dx.doi.org/10.1186/s13058-016-0749-6