TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway

OBJECTIVE: Obesity and type 2 diabetes (T2D) lead to various life-threatening diseases such as coronary heart disease, stroke, osteoarthritis, asthma, and neurodegeneration. Therefore, extensive research is ongoing to identify novel pathways that can be targeted in obesity/T2D. Deletion of the inosi...

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Detalles Bibliográficos
Autores principales: Ghoshal, Sarbani, Zhu, Qingzhang, Asteian, Alice, Lin, Hua, Xu, Haifei, Ernst, Glen, Barrow, James C., Xu, Baoji, Cameron, Michael D., Kamenecka, Theodore M., Chakraborty, Anutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034689/
https://www.ncbi.nlm.nih.gov/pubmed/27689003
http://dx.doi.org/10.1016/j.molmet.2016.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034689/
https://www.ncbi.nlm.nih.gov/pubmed/27689003
http://dx.doi.org/10.1016/j.molmet.2016.08.008

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