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Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis

This study aimed to derive quantitative abundance values for key hepatic transporters suitable for in vitro–in vivo extrapolation within a physiologically based pharmacokinetic modeling framework. A meta-analysis was performed whereby data on abundance measurements, sample preparation methods, and d...

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Detalles Bibliográficos
Autores principales: Burt, Howard J., Riedmaier, Arian Emami, Harwood, Matthew D., Crewe, H. Kim, Gill, Katherine L., Neuhoff, Sibylle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034697/
https://www.ncbi.nlm.nih.gov/pubmed/27493152
http://dx.doi.org/10.1124/dmd.116.071183