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Resident microglia, rather than blood‐derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia‐ischemia

The mechanisms of neuronal injury after hypoxia–ischemia (HI) are different in the immature and the adult brain, but microglia activation has not been compared. The purpose of this study was to phenotype resident microglia and blood‐derived macrophages in the hippocampus after HI in neonatal (postna...

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Detalles Bibliográficos
Autores principales: Umekawa, Takashi, Osman, Ahmed M., Han, Wei, Ikeda, Tomoaki, Blomgren, Klas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034822/
https://www.ncbi.nlm.nih.gov/pubmed/26179283
http://dx.doi.org/10.1002/glia.22887