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Functionalized immunostimulating complexes with protein A via lipid vinyl sulfones to deliver cancer drugs to trastuzumab-resistant HER2-overexpressing breast cancer cells

BACKGROUND: Around 20%–30% of breast cancers overexpress the proto-oncogene human epidermal growth receptor 2 (HER2), and they are characterized by being very invasive. Therefore, many current studies are focused on testing new therapies against tumors that overexpress this receptor. In particular,...

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Detalles Bibliográficos
Autores principales: Rodríguez-Serrano, Fernando, Mut-Salud, Nuria, Cruz-Bustos, Teresa, Gomez-Samblas, Mercedes, Carrasco, Esther, Garrido, Jose Manuel, López-Jaramillo, F Javier, Santoyo-Gonzalez, Francisco, Osuna, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034911/
https://www.ncbi.nlm.nih.gov/pubmed/27698563
http://dx.doi.org/10.2147/IJN.S112560