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Reduced Plasmodium Parasite Burden Associates with CD38(+) CD4(+) T Cells Displaying Cytolytic Potential and Impaired IFN-γ Production
Using a unique resource of samples from a controlled human malaria infection (CHMI) study, we identified a novel population of CD4(+) T cells whose frequency in the peripheral blood was inversely correlated with parasite burden following P. falciparum infection. These CD4(+) T cells expressed the mu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035011/ https://www.ncbi.nlm.nih.gov/pubmed/27662621 http://dx.doi.org/10.1371/journal.ppat.1005839 |