Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression

The cytoplasmic viral sensor retinoic acid-inducible gene-I (RIG-I), which is also known as an IFN-stimulated gene (ISG), senses viral RNA to activate antiviral signaling. It is therefore thought that RIG-I is regulated in a STAT1-dependent manner. Although RIG-I-mediated antiviral signaling is indi...

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Detalles Bibliográficos
Autores principales: Hayakari, Ryo, Matsumiya, Tomoh, Xing, Fei, Yoshida, Hidemi, Hayakari, Makoto, Imaizumi, Tadaatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035021/
https://www.ncbi.nlm.nih.gov/pubmed/27662626
http://dx.doi.org/10.1371/journal.pone.0163520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035021/
https://www.ncbi.nlm.nih.gov/pubmed/27662626
http://dx.doi.org/10.1371/journal.pone.0163520

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