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An Advanced Model to Precisely Estimate the Cell-Free Fetal DNA Concentration in Maternal Plasma
BACKGROUND: With the speedy development of sequencing technologies, noninvasive prenatal testing (NIPT) has been widely applied in clinical practice for testing for fetal aneuploidy. The cell-free fetal DNA (cffDNA) concentration in maternal plasma is the most critical parameter for this technology...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035032/ https://www.ncbi.nlm.nih.gov/pubmed/27662469 http://dx.doi.org/10.1371/journal.pone.0161928 |