Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models

Current treatments available for African sleeping sickness or human African trypanosomiasis (HAT) are limited, with poor efficacy and unacceptable safety profiles. Here, we report a new approach to address treatment of this disease based on the use of compounds that bind to parasite surface glycans...

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Detalles Bibliográficos
Autores principales: Castillo-Acosta, Víctor M., Ruiz-Pérez, Luis M., Etxebarria, Juan, Reichardt, Niels C., Navarro, Miguel, Igarashi, Yasuhiro, Liekens, Sandra, Balzarini, Jan, González-Pacanowska, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035034/
https://www.ncbi.nlm.nih.gov/pubmed/27662652
http://dx.doi.org/10.1371/journal.ppat.1005851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035034/
https://www.ncbi.nlm.nih.gov/pubmed/27662652
http://dx.doi.org/10.1371/journal.ppat.1005851

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