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Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose

Type 1 diabetes occurs due to the autoimmune destruction of pancreatic β-cells in islets. Transplantation of islets is a promising option for the treatment of patients with type 1 diabetes that experience hypoglycemic unawareness despite maximal care, but the present shortage of donor islets hampers...

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Detalles Bibliográficos
Autores principales: Saitoh, Issei, Sato, Masahiro, Soda, Miki, Inada, Emi, Iwase, Yoko, Murakami, Tomoya, Ohshima, Hayato, Hayasaki, Haruaki, Noguchi, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035045/
https://www.ncbi.nlm.nih.gov/pubmed/27662374
http://dx.doi.org/10.1371/journal.pone.0163580