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Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose
Type 1 diabetes occurs due to the autoimmune destruction of pancreatic β-cells in islets. Transplantation of islets is a promising option for the treatment of patients with type 1 diabetes that experience hypoglycemic unawareness despite maximal care, but the present shortage of donor islets hampers...
Autores principales: | Saitoh, Issei, Sato, Masahiro, Soda, Miki, Inada, Emi, Iwase, Yoko, Murakami, Tomoya, Ohshima, Hayato, Hayasaki, Haruaki, Noguchi, Hirofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035045/ https://www.ncbi.nlm.nih.gov/pubmed/27662374 http://dx.doi.org/10.1371/journal.pone.0163580 |
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