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A Broad Set of Chromatin Factors Influences Splicing

Several studies propose an influence of chromatin on pre-mRNA splicing, but it is still unclear how widespread and how direct this phenomenon is. We find here that when assembled in vivo, the U2 snRNP co-purifies with a subset of chromatin-proteins, including histones and remodeling complexes like S...

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Detalles Bibliográficos
Autores principales: Allemand, Eric, Myers, Michael P., Garcia-Bernardo, Jose, Harel-Bellan, Annick, Krainer, Adrian R., Muchardt, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035054/
https://www.ncbi.nlm.nih.gov/pubmed/27662573
http://dx.doi.org/10.1371/journal.pgen.1006318