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Regulatory T-cells are essential to promote proper CD4 T-cell priming upon mucosal infection

Regulatory T-cells (Tregs) limit autoimmunity and immunopathology using a variety of suppressive mechanisms, but their roles during pathogen-directed immune responses remain unclear. Following Herpes Simplex virus-2 (HSV-2) infection, mice lacking Tregs fail to control viral replication, pointing to...

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Detalles Bibliográficos
Autores principales: Soerens, Andrew G., Da Costa, Andreia, Lund, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035160/
https://www.ncbi.nlm.nih.gov/pubmed/27007674
http://dx.doi.org/10.1038/mi.2016.19