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Critical role of caspase-8–mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis
Allergic asthma is a chronic inflammatory disorder of the airways that affects more than 300 million people worldwide. The pro-inflammatory cytokines IL-1α and IL-1β play essential roles in the pathogenesis of asthma. However, the mechanisms underlying the production of IL-1 cytokines in allergic as...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035164/ https://www.ncbi.nlm.nih.gov/pubmed/27007676 http://dx.doi.org/10.1038/mi.2016.25 |