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Critical role of caspase-8–mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis

Allergic asthma is a chronic inflammatory disorder of the airways that affects more than 300 million people worldwide. The pro-inflammatory cytokines IL-1α and IL-1β play essential roles in the pathogenesis of asthma. However, the mechanisms underlying the production of IL-1 cytokines in allergic as...

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Detalles Bibliográficos
Autores principales: Qi, Xiaopeng, Gurung, Prajwal, Malireddi, R. K. Subbarao, Karmaus, Peer W. F., Sharma, Deepika, Vogel, Peter, Chi, Hongbo, Green, Douglas R., Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035164/
https://www.ncbi.nlm.nih.gov/pubmed/27007676
http://dx.doi.org/10.1038/mi.2016.25