Cargando…
Critical role of caspase-8–mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis
Allergic asthma is a chronic inflammatory disorder of the airways that affects more than 300 million people worldwide. The pro-inflammatory cytokines IL-1α and IL-1β play essential roles in the pathogenesis of asthma. However, the mechanisms underlying the production of IL-1 cytokines in allergic as...
Autores principales: | Qi, Xiaopeng, Gurung, Prajwal, Malireddi, R. K. Subbarao, Karmaus, Peer W. F., Sharma, Deepika, Vogel, Peter, Chi, Hongbo, Green, Douglas R., Kanneganti, Thirumala-Devi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035164/ https://www.ncbi.nlm.nih.gov/pubmed/27007676 http://dx.doi.org/10.1038/mi.2016.25 |
Ejemplares similares
-
IL-10 engages macrophages to shift Th17 cytokine dependency and
pathogenicity during T cell-mediated colitis
por: Li, Bofeng, et al.
Publicado: (2015) -
Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation
por: Gurung, Prajwal, et al.
Publicado: (2015) -
TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2018) -
Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection
por: Malireddi, R. K. Subbarao, et al.
Publicado: (2013) -
Hierarchical Cell Death Program Disrupts the Intracellular Niche Required for Burkholderia thailandensis Pathogenesis
por: Place, David E., et al.
Publicado: (2021)