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Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase
Bempedoic acid (ETC-1002), a novel therapeutic approach for low-density lipoprotein cholesterol (LDL-C) lowering, inhibits ATP citrate lyase (ACL), an enzyme involved in fatty acid and cholesterol synthesis. Although rodent studies suggested potential effects of ACL inhibition on both fatty acid and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035316/ https://www.ncbi.nlm.nih.gov/pubmed/27663902 http://dx.doi.org/10.1007/s11883-016-0611-4 |