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KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression()

Our studies investigating the existence of tumor-initiating cell (TIC) populations in human esophageal squamous cell carcinoma (ESCC) had identified a subpopulation of cells isolated from ESCC patient-derived tumor specimens marked by an ALDH(bri+) phenotype bear stem cell-like features. Importantly...

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Detalles Bibliográficos
Autores principales: Yuan, Xiang, Kong, Jinyu, Ma, Zhikun, Li, Na, Jia, Ruinuo, Liu, Yiwen, Zhou, Fuyou, Zhan, Qimin, Liu, Gang, Gao, Shegan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035342/
https://www.ncbi.nlm.nih.gov/pubmed/27742014
http://dx.doi.org/10.1016/j.neo.2016.08.005