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PTB and TIAR binding to insulin mRNA 3′- and 5′UTRs; implications for insulin biosynthesis and messenger stability

OBJECTIVES: Insulin expression is highly controlled on the posttranscriptional level. The RNA binding proteins (RBPs) responsible for this result are still largely unknown. METHODS AND RESULTS: To identify RBPs that bind to insulin mRNA we performed mass spectrometry analysis on proteins that bound...

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Detalles Bibliográficos
Autores principales: Fred, Rikard G., Mehrabi, Syrina, Adams, Christopher M., Welsh, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035359/
https://www.ncbi.nlm.nih.gov/pubmed/27699280
http://dx.doi.org/10.1016/j.heliyon.2016.e00159