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Amino acid substitutions involved in the adaptation of a novel highly pathogenic H5N2 avian influenza virus in mice

BACKGROUND: H5N2 avian influenza viruses (AIVs) can infect individuals that are in frequent contact with infected birds. In 2013, we isolated a novel reassortant highly pathogenic H5N2 AIV strain [A/duck/Zhejiang/6DK19/2013(H5N2) (6DK19)] from a duck in Eastern China. This study was undertaken to un...

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Detalles Bibliográficos
Autores principales: Wu, Haibo, Peng, Xiuming, Peng, Xiaorong, Wu, Nanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035443/
https://www.ncbi.nlm.nih.gov/pubmed/27663652
http://dx.doi.org/10.1186/s12985-016-0612-5