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The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus

BACKGROUND: The complex interplay between viral replication and host immune response during infection remains poorly understood. While many viruses are known to employ anti-immune strategies to facilitate their replication, highly pathogenic virus infections can also cause an excessive immune respon...

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Detalles Bibliográficos
Autores principales: McDermott, Jason E., Mitchell, Hugh D., Gralinski, Lisa E., Eisfeld, Amie J., Josset, Laurence, Bankhead, Armand, Neumann, Gabriele, Tilton, Susan C., Schäfer, Alexandra, Li, Chengjun, Fan, Shufang, McWeeney, Shannon, Baric, Ralph S., Katze, Michael G., Waters, Katrina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035469/
https://www.ncbi.nlm.nih.gov/pubmed/27663205
http://dx.doi.org/10.1186/s12918-016-0336-6