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Leptin decreases the expression of low-density lipoprotein receptor via PCSK9 pathway: linking dyslipidemia with obesity

BACKGROUND: Previous studies have suggested that people with obesity showed elevated serum levels of leptin as well as lipid dysfunction and proprotein convertase subtilisin/kexin type 9 (PCSK9) played an important role in the regulation of lipid metabolism recently. The aim of this study was to det...

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Detalles Bibliográficos
Autores principales: Du, Ying, Li, Sha, Cui, Chuan-Jue, Zhang, Yan, Yang, Sheng-Hua, Li, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035475/
https://www.ncbi.nlm.nih.gov/pubmed/27663646
http://dx.doi.org/10.1186/s12967-016-1032-4