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Why Is there a Limit to the Changes in Myofilament Ca(2+)-Sensitivity Associated with Myopathy Causing Mutations?
Mutations in striated muscle contractile proteins have been found to be the cause of a number of inherited muscle diseases; in most cases the mechanism proposed for causing the disease is derangement of the thin filament-based Ca(2+)-regulatory system of the muscle. When considering the results of e...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035734/ https://www.ncbi.nlm.nih.gov/pubmed/27725803 http://dx.doi.org/10.3389/fphys.2016.00415 |