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Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss

Characteristic features of Alzheimer’s disease are memory loss, plaques resulting from abnormal processing of amyloid precursor protein (APP), and presence of neurofibrillary tangles and dystrophic neurites containing hyperphosphorylated tau. Currently, it is not known what links these abnormalities...

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Detalles Bibliográficos
Autores principales: Tiwari, Sachin Suresh, Mizuno, Keiko, Ghosh, Anshua, Aziz, Wajeeha, Troakes, Claire, Daoud, Jason, Golash, Vidushi, Noble, Wendy, Hortobágyi, Tibor, Giese, Karl Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035822/
https://www.ncbi.nlm.nih.gov/pubmed/27524794
http://dx.doi.org/10.1093/brain/aww205