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Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss
Characteristic features of Alzheimer’s disease are memory loss, plaques resulting from abnormal processing of amyloid precursor protein (APP), and presence of neurofibrillary tangles and dystrophic neurites containing hyperphosphorylated tau. Currently, it is not known what links these abnormalities...
Autores principales: | Tiwari, Sachin Suresh, Mizuno, Keiko, Ghosh, Anshua, Aziz, Wajeeha, Troakes, Claire, Daoud, Jason, Golash, Vidushi, Noble, Wendy, Hortobágyi, Tibor, Giese, Karl Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035822/ https://www.ncbi.nlm.nih.gov/pubmed/27524794 http://dx.doi.org/10.1093/brain/aww205 |
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