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Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis

The PRL phosphatases are oncogenic when overexpressed but their in vivo biological function is less well understood. Previous gene deletion study revealed a role for PRL2 in spermatogenesis. We report here the first knockout mice lacking PRL1, the most related homolog of PRL2. We found that loss of...

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Detalles Bibliográficos
Autores principales: Bai, Yunpeng, Zhou, Hong-Ming, Zhang, Lujuan, Dong, Yuanshu, Zeng, Qi, Shou, Weinian, Zhang, Zhong-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035919/
https://www.ncbi.nlm.nih.gov/pubmed/27666520
http://dx.doi.org/10.1038/srep34211