Exploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screening

TRPV1 is a polymodal nociceptor for diverse physical and chemical stimuli that interact with different parts of the channel protein. Recent cryo-EM studies revealed detailed channel structures, opening the door for mapping structural elements mediating activation by each stimulus. Towards this goal,...

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Detalles Bibliográficos
Autores principales: Ma, Linlin, Yang, Fan, Vu, Simon, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035920/
https://www.ncbi.nlm.nih.gov/pubmed/27666400
http://dx.doi.org/10.1038/srep33827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035920/
https://www.ncbi.nlm.nih.gov/pubmed/27666400
http://dx.doi.org/10.1038/srep33827

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