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Exploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screening

TRPV1 is a polymodal nociceptor for diverse physical and chemical stimuli that interact with different parts of the channel protein. Recent cryo-EM studies revealed detailed channel structures, opening the door for mapping structural elements mediating activation by each stimulus. Towards this goal,...

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Detalles Bibliográficos
Autores principales:	Ma, Linlin, Yang, Fan, Vu, Simon, Zheng, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035920/ https://www.ncbi.nlm.nih.gov/pubmed/27666400 http://dx.doi.org/10.1038/srep33827

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