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How Polyomaviruses Exploit the ERAD Machinery to Cause Infection

To infect cells, polyomavirus (PyV) traffics from the cell surface to the endoplasmic reticulum (ER) where it hijacks elements of the ER-associated degradation (ERAD) machinery to penetrate the ER membrane and reach the cytosol. From the cytosol, the virus transports to the nucleus, enabling transcr...

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Detalles Bibliográficos
Autores principales: Dupzyk, Allison, Tsai, Billy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035956/
https://www.ncbi.nlm.nih.gov/pubmed/27589785
http://dx.doi.org/10.3390/v8090242