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Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways

Evolutionally conserved Wnt, Hedgehog (Hh) and Notch morphogen pathways play essential roles in the development, homeostasis and pathogenesis of multicellular organisms. Nevertheless, mechanisms that intracellularly coordinate these signal inputs remain poorly understood. Here we found that parafibr...

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Detalles Bibliográficos
Autores principales: Kikuchi, Ippei, Takahashi-Kanemitsu, Atsushi, Sakiyama, Natsuki, Tang, Chao, Tang, Pei-Jung, Noda, Saori, Nakao, Kazuki, Kassai, Hidetoshi, Sato, Toshiro, Aiba, Atsu, Hatakeyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036006/
https://www.ncbi.nlm.nih.gov/pubmed/27650679
http://dx.doi.org/10.1038/ncomms12887