Gender effects of single nucleotide polymorphisms and miRNAs targeting clock-genes in metastatic colorectal cancer patients (mCRC)

The circadian system is composed of a set of clock-genes including PERIOD, CLOCK, BMAL1 and CRY. Disrupting this system promotes cancer development and progression. The expression levels of miR-206, miR-219, miR-192, miR-194 and miR-132 regulating clock-genes and three functional polymorphisms rs111...

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Detalles Bibliográficos
Autores principales: Garufi, Carlo, Giacomini, Elisa, Torsello, Angela, Sperduti, Isabella, Melucci, Elisa, Mottolese, Marcella, Zeuli, Massimo, Ettorre, Giuseppe Maria, Ricciardi, Teresa, Cognetti, Francesco, Magnani, Mauro, Ruzzo, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036027/
https://www.ncbi.nlm.nih.gov/pubmed/27666868
http://dx.doi.org/10.1038/srep34006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036027/
https://www.ncbi.nlm.nih.gov/pubmed/27666868
http://dx.doi.org/10.1038/srep34006

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